一．个人简介
徐勇前，博士，教授，博士生导师。国家自然科学基金通讯评审人，教育部学位中心通讯评议专家，国家重点研发计划评审专家，中国化学会高级会员，中国感光学会光学传感与诊疗专委会委员。Advanced Materials, Chemical Science, Chemical Communications, Biomacromolecules, Biosensors and Bioelectronics, Chemical Engineering Journal等国际学术期刊审稿人。2015年指导的大学生科创项目获全国“挑战杯”三等奖。2019年获校级教学成果二等奖（1/5）。
二、学习与工作经历
2000年9月~2006年12月 大连理工大学应用化学专业，博士；
2008年2月~2011年9月 美国阿克伦大学有机化学系，博士后；
2011年9月~2016年12月西北农林科技大学理学院，副教授；
2017年1月~至今西北农林科技大学化学与药学院，教授；
三、研究课题
1. 国家自然科学基金面上项目，基于级联蛋白信号放大响应构建近红外荧光检测生物酶的染料组装体，65万，21978241，2020.01-2023.12
2. 国家自然科学基金面上项目，肝细胞线粒体内双活性氧多通道探针研究，64万，21676218，2017.01-2020.12；
3. 国家自然科学基金面上项目，近红外菁染料聚集调控及其用于生物分子检测研究，86万，21476185，2015.01-2018.12；
4. 国家自然科学基金青年项目，可用于诊断与治疗一体化的新型纳米高分子聚合物“点”的构建，25万，21206137，2013.01-2015.12；
5. 陕西省科技计划社会发展领域项目，基于葡萄糖检测和胰岛素智能释放的分子组装体用于糖尿病的诊断和精准治疗研究，6万，2023-YBSF-224，2023.01-2024.12。
6. 陕西省自然科学基础研究计划面上项目，肝细胞线粒体内双活性氧物质的多通道检测研究，3万，2019JM-173，2019.01-2020.12。
7. 陕西省社会发展科技攻关项目，功能纳米材料用于恶性肿瘤的诊疗，7万，2014K11-01-02-06，2014.01-2015.12。
8. 西北农林科技大学引进人才科研启动专项。
四、研究领域
荧光染料及其体内外应用（分析化学与应用化学）
1、新型荧光探针的设计合成、结构与性能调控及生物成像与动态监测分析；
2、发光纳米材料与多功能复合材料的设计构筑及其生物传感与刺激响应应用；
3、纳米靶向药物递送系统与光动力/光热协同治疗体系的构建及诊疗一体化应用。
五、开设课程
为本科生讲授《分析化学》、《分析化学实验》
六、主要科研成果与学术论文
1. Qi Zhang, Lan Yu, Weiqiang Han, Li Yang, Hongjuan Li, Shiguo Sun and Yongqian Xu*, A self-calibrating sensing platform based on amine-responsive excitation wavelength-dependent fluorescent polymers for real-time and visual detection of food freshness, Adv. Funct. Mater., 2024, 34, 2410000.
2. Zongyan Quan, Zhiping Chen, Hongjuan Li, Shiguo Sun, and Yongqian Xu*, A hydrogel sensor based on cellulose nanofiber/polyvinyl alcohol with colorimetric-fluorescent bimodality for non-invasive detection of urea in sweat, Int. J. Biol. Macromol., 2024, 276, 133760.
3. Qi Zhang, Zhidong Chang, Weiqiang Han, Chaofan Wang, Guoxin Liu, Hongjuan Li, Shiguo Sun and Yongqian Xu*, Multidimension-regulated dynamic timing control over multicolor emission of host-guest assemblies for information encryption and advanced anti-counterfeiting, Adv. Opt. Mater., 2024, 12(19), 2400231.
4. Li Yang, Qi Zhang, Yatuan Ma, Hongjuan Li, Shiguo Sun, Yongqian Xu*, Stimulus-responsive room-temperature phosphorescence with tunable color for time-resolved advanced dynamic anti-counterfeiting, Chem. Eng. J., 2024, 490, 151679.
5. Yuhuan Zhang, Xiaoli Luo, Hongjuan Li, Shiguo Sun, and Yongqian Xu*, Host-Guest supramolecular Cubes: A versatile engineering system of squaraine and Cuburbit[8]uril for selective fluorescence imaging and enhanced photodynamic therapy in tumor cells, Chem. Eng. J., 2024, 488, 150979.
6. Wei-Nan Zhao#, Jianghao Xing#, Min Wang, Hongjuan Li, Shiguo Sun, Xianwen Wang* and Yongqian Xu*, Engineering a hyaluronic acid-encapsulated tumor-targeted nanoplatform with sensitized chemotherapy and a photothermal effect for enhancing tumor therapy, Int. J. Biol. Macromol., 2024, 264, 130785.
7. Yuchen huyan, Xiaojing Nan, Hongjuan Li, Shiguo Sun and Yongqian Xu*, A novel FA1-targeting fluorescent probe for specific discrimination and identification of human serum albumin from bovine serum albumin, Chem. Commun., 2024, 60, 3810-3813.
8. Wei-Nan Zhao, Hongjuan Li, Shiguo Sun and Yongqian Xu*, The construction of hierarchical assemblies with in situ generation of chemotherapy drugs to enhance the efficacy of chemodynamic therapy for multi-modal anti-tumor treatments, J. Mater. Chem. B, 2023, 11, 11044-11051. (front cover)
9. Zongyan Quan, Qi Zhang, Hongjuan Li, Shiguo Sun, and Yongqian Xu*, Fluorescent cellulose-based materials for information encryption and anti-counterfeiting, Coordin. Chem. Rev., 2023, 493, 215287.
10. Ying Han#, Canxia Luo#, Zongyan Quan, Hongjuan Li, Shiguo Sun, and Yongqian Xu*, New “destruction seek to survive” strategy based on a serum albumin assembly with a squaraine molecule for the detection of peroxynitrite, Anal. Chem., 2023, 95, 7278-7285.
11. Qi Zhang, Li Yang, Yanfei Gao, Yanping Xiang, Hongjuan Li, Shiguo Sun and Yongqian Xu*, Multi-color solid-state photoluminescence from orthogonally multi-stimuli-responsive organic molecule for advanced information storage and encryption, Chem. Eng. J., 2023, 459, 141666.
12. Canxia Luo, Qi Zhang, Shiguo Sun, Hongjuan Li, Yongqian Xu*, Research progress of auxiliary groups in improving the performance of fluorescent probes, Chem. Commun., 2023, 59, 2199-2207.
13. Li Yang, Qi Zhang, Yueyue Huang, Canxia Luo, Zongyan Quan, Hongjuan Li, Shiguo Sun, Yongqian Xu*, A sequential dual-lock strategy for generation of room-temperature phosphorescence of boron doped carbon dots for dynamic anti-counterfeiting, J. Colloid Interface Sci., 2023, 632, 129-139.
14. Wei-Nan Zhao, Min Wang, Chen Zhang, Shiguo Sun and Yongqian Xu*, Cancer cell membrane targeting and red light-triggered carbon monoxide (CO) release for enhanced chemotherapy, Chem. Commun., 2022, 58, 8512-8515.
15. Yuhuan Zhang, Hongjuan Li, Shiguo Sun and Yongqian Xu*, An ESIPT fluorescent probe based on Staudinger reaction for detection of triphenylphosphine and tetrakis(triphenyl-phosphine)palladium, Sens. Actuators B-Chem., 2022, 358, 131506.
16. Qi Zhang, Li Yang, Ying Han, Zhiyu Wang, Hongjuan Li, Shiguo Sun and Yongqian Xu*, A pH-sensitive ESIPT molecule with aggregation-induced emission and tunable solid-state fluorescence multicolor for anti-counterfeiting and food freshness detection, Chem. Eng. J., 2022, 428, 130986.
17. Xiaojing Nan, Yuchen Huyan, Hongjuan Li, Shiguo Sun, Yongqian Xu*, Reaction-based fluorescent probes for Hg2+, Cu2+ and Fe3+/Fe2+, Coordin. Chem. Rev., 2021, 426, 213580.
18. Dejia Wang, Yuchen Huyan, Xiaojing Nan, Hongjuan Li, Shiguo Sun, Yongqian Xu*, Product-boosted fluorescence signal: a new approach for designing small-molecule probes for detection of peroxynitrite, Chem. Commun., 2020, 56, 7925-7928.
19. Dejia Wang, Hongjuan Li, Shiguo Sun, Yongqian Xu*, Cyanide boosting copper catalysis: a mild approach to fluorescent benzazole derivatives from nonemissive Schiff bases in biological media, Org. Lett., 2020, 22, 3361-3366.
20. Ying Wu#, Yuhuan Zhang#, Lan Wang, Yuchen Huyan, Hongjuan Li, Zhichao Pei, Yanfeng Tang, Shiguo Sun, Yongqian Xu*, A simple ratiometric fluorescent sensor selectively compatible of different combinations of characteristic groups for identification of glutathione, cysteine and homocysteine, Sens. Actuators B-Chem., 2020, 302, 127181.
21. 徐勇前，杨历，孙世国，王军红，一种水和加热连续刺激响应的磷光碳量子点的制备及应用，授权专利，ZL202210053809.5
22. 徐勇前，张奇，杨历，孙世国，王军红，苯并噻唑衍生物在防伪和加密上的应用，授权专利，ZL202210081292.0
23. 徐勇前，杨历，一种磷酸根响应的碳量子点的制备及其用于指纹荧光识别的应用，授权专利，ZL202011272121.3
24. 徐勇前，张奇，苯并噻唑衍生物在防伪和食品检测上的应用，授权专利，ZL202011272224.X
25.徐勇前，孙世国，吴影，一种以噻唑为母体的丙烯酰酯类化合物作为荧光探针的应用及其制备方法，授权专利，ZL201811260252.2
26. 徐勇前，孙世国，王德佳，李红娟，赵宏伟，一类席夫碱化合物作为氰根离子和铜离子荧光探针的应用，授权专利，ZL201710341562.6.
27. 徐勇前，孙世国，王德佳，赵宏伟，二酚化合物与2-醛基苯硼酸形成的自组装及其作为荧光探针的应用，授权专利，ZL201710690352.8.
28. 徐勇前，孙世国，陈晖，三磷酸腺苷近红外荧光探针的制备方法，授权专利，ZL201610066928.9.
29. 徐勇前，孙世国，赵宏伟，一种荧光染料及其应用，授权专利，ZL201610486134.8.
30. 徐勇前，孙世国，贺卿原，缓冲水溶液中检测亲和素的近红外荧光探针的制备方法，授权专利，ZL201510141575.X.
七、联系方式
通讯地址：西北农林科技大学（北校区）化学与药学院（C406）
邮编：712100
邮箱：xuyq@nwsuaf.edu.cn
欢迎对研究方向感兴趣的本科生和研究生加盟课题组！
