一、个人简介
李定，博士，讲师，硕士研究生导师，男，1984年2月生于湖北武汉。
2004.09--2008.06年 华中师范大学化学学院，获化学和生物技术双学士学位。
2008.09--2013.06年 华中师范大学化学学院，农药与化学生物学教育部重点实验室，硕博连读，获有机化学理学博士学位。
2013.12--2015.12 西北农林科技大学理学院从事博士后研究。
2013.07--至今西北农林科技大学化学与药学学院工作。
二、科研课题
主持：1）国家自然科学基金（No. 21502152）21万
2）陕西省自然科学基础研究计划（No.2014JQ2075）3万
3）中国博士后科学基金面上资助（NO.2014M562452）5万
4）陕西省博士后科研项目资助 2万
5) 中央高校基本科研业务费(No. 2452016092)12万
6）西北农林科技大学博士科研启动基金5万
7）陕西省博士科研启动基金 5万
三、研究领域
主要研究方向：计算机辅助药物设计、靶向蛋白的抑制剂（药物）设计和活性筛选。
四、开设课程
《有机化学》、《有机化学实验》、《分子模拟与计算机辅助药物设计》和《无机化学实验》
五、主要科研成果与学术论文
Ding Li(*,#); Bo Chi; Wei-Wei Wang; Jin-Ming Gao (*); Jian Wan. Exploring the possible binding mode of trisubstituted benzimidazoles analogues in silico for novel drug designtargeting Mtb FtsZ. Medicinal Chemistry Research . 2017, 26 (1): 153–169
Sun Yao(#); Zhang Rui(#); Li Ding(#); Feng Lingling(*); Wu Di; Feng Lina; Huang Peipei; Ren Yanliang; Feng JiangTao; Xiao San; Wan Jian(*). Pharmacophore-Based Virtual Screening and Experimental Validation of Novel Inhibitors against Cyanobacterial Fructose-1,6- /Sedoheptulose-1,7-bisphosphatase. Journal of Chemical Information and Modeling . 2014，54（3）：894-901.
Feng Lingling(#); Sun Yao(#); Deng Hui(#); Li Ding(#); Wan Jian(*); Wang Xiaofeng; Wang Weiwei; Liao Xun; Ren Yanliang; Hu Xiaopeng(*). Structural and Biochemical Characterization of Fructose-1,6/Sedoheptulose-1,7-bisphosphatase from the Cyanobacterium Synechocystis Strain 6803. FEBS Journal . 2014, 281 (3)：916-926
Zhang Lili(#); Li Ding(#); Xu Rui; Zheng Sichun; He Hongwu; Wan Jian(*); Feng Qili(*).Structural and Functional Analyses of a Sterol Carrier Protein in Spodoptera litura . PLos One . 2014, 9 (1)
Li Ding(#); Han Xinya(#); Tu Qidong(#); Feng Liugling; Wu Di; Sun Yao; Chen Haifeng; Li Yongjian; Ren Yanliang(*); Wan Jian(*).Structure-Based Design and Synthesis of Novel Dual-Target Inhibitors against Cyanobacterial Fructose-1,6-Bisphosphate Aldolase and Fructose-1,6-Bisphosphatase. Journal of Agricultural and Food Chemistry . 2013, 61 (31): 7453-7461.
Tu Qi-Dong(#); Li Ding(#); Sun Yao(#); Han Xin-Ya; Yi Fan; Sha Yibamu; Ren Yan-Liang; Ding Ming-Wu; Feng Ling-Ling(*); Wan Jian(*). Design and Syntheses of Novel N '-((4-oxo-4H-chromen-3-yl) methylene) Benzohydrazide as Inhibitors of Cyanobacterial Fructose-1,6-/Sedoheptulose-1,7-bisphosphatase. Bioorganic & Medicinal Chemistry . 2013, 21 (11): 2826 -2831.
Ding Li(#), Jie Gui, Yongjian Li, Lingling Feng, Xinya Han, Yao Sun, Tinglin Sun, Zhigang Chen,Yi Cao, Yang Zhang, Li Zhou, Xiaopeng Hu, Yanliang Ren(*) and Jian Wan(*). Structure-Based Design and Screen of Novel Inhibitors for Class II 3-Hydroxy -3-methylglutaryl Coenzyme A Reductase from Streptococcus Pneumoniae . Journal of Chemical Information and Modeling. 2012, 52 (7): 1833-1841.
Qingye Zhang(#), Ding Li(#), Pei Wei, Jie Zhang, Jian Wan(*), Yangliang Ren, Zhigang Chen, Deli Liu, Ziniu Yu, Lingling Feng(*). Structure-based Rational Screening of Novel Hit Compounds with Structural Diversity for Cytochrome P450 Sterol 14a-demethylase from Penicillium digitatum, Journal of Chemical Information and Modeling. 2010, 50 (2): 317-325.
Yao Sun, Xun Liao, Ding Li, Lingling Feng(*), Jun Li, Xiaofeng Wang, Jing Jin, Fan Yi, Li Zhou, Jian Wan(*). Study on the interaction between cyanobacteria FBP/SBPase and metal ions. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2012, 89: 337-344.
Lingling Feng(*,#), Hui Li, Jingmei Jiao, Ding Li, Li Zhou, Jian Wan and Yangsheng Li(*). Reduction in SBPase Activity by Antisense RNA in Transgenic Rice Plants: Effect on Photosynthesis, Growth, and Biomass Allocation at Different Nitrogen Levels Journal of Plant Biology , 2009, 52 (5): 382–394.
六、联系方式
通讯地址：西北农林科技大学理学院 E214
邮编：712100
邮箱：jbolid@nwsuaf.edu.cn
