一、个人简介
刘晓玲,理学博士,青年教授,博士生导师。2018年6月毕业于中国科学院生态环境研究中心,获得理学博士学位。2018-2022年,在陕西师范大学化学化工学院从事博士后研究工作。2022年加入西北农林科技大学化学与药学院。
二、科研项目
1. 西北农林科技大学引进人才启动经费(2023-2027),主持
2. 国家自然科学基金青年科学基金项目(2022-2024),主持
3. 陕西省自然科学基础研究计划,一般项目(青年)(2020-2021),主持
4. 中央高校基本科研业务费专项资金项目(2019-2020;2021-2022),主持
三、研究领域
生化分析与分子诊断
核酸分析化学
生物传感新原理与新方法
四、开设课程
《分析化学》、《分析化学实验》、《化学生物学》
五、主要科研成果与学术论文
1. Xiaoling Liu#, Weiyi Lai#, Yao Li#, Shaokun Chen, Baodong Liu, Ning Zhang, Jiezhen Mo, Cong Lyu, Jing Zheng, Ya-Rui Du, Guibin Jiang, Guo-Liang Xu, Hailin Wang*. N6-methyladenine is incorporated into mammalian genome by DNA polymerase. Cell Research 2021, 31, 94–97.
2. Xiaoling Liu*, Xinyue Kang, Chao Lei, Wei Ren, Chenghui Liu*. Programming the trans -cleavage activity of CRISPR-Cas13a by single-strand DNA blocker and its biosensing application. Analytical Chemistry 2022, 94, 3987–3996.
3. Gaoting Wang, Weimin Tian, Xiaoling Liu*, Wei Ren, Chenghui Liu*. New CRISPR-derived microRNA sensing mechanism based on Cas12a self-powered and rolling circle transcription-unleashed real-time crRNA recruiting. Analytical Chemistry 2020, 92, 6702–6708.
4. Xiaoling Liu, Weiyi Lai, Ning Zhang, Hailin Wang*. Predominance of N6-methyladenine-specific DNA fragments enriched by multiple immunoprecipitation. Analytical Chemistry 2018, 90, 5546–5551.
5. Xinyue Kang, Chao Lei, Jingjing Shi, Xiaoling Liu*, Wei Ren, Chenghui Liu*. A versatile CRISPR/Cas12a-based biosensing platform coupled with a target-protected transcription strategy. Biosensors and Bioelectronics 2023, 219, 114801.
6. Weimin Tian, Xiaoling Liu*, Gaoting Wang, Chenghui Liu*. A hyperbranched transcription-activated CRISPR-Cas12a signal amplification strategy for sensitive microRNA sensing. Chemical Communications 2020, 56, 13445–13448.
7. Gaoting Wang, Wenjiao Fan, Wei Ren, Xiaoling Liu*, Chenghui Liu*. High-sensitive sensing of plant microRNA by integrating click chemistry with an unusual on-bead poly(T)-promoted transcription amplification. Analytica Chimica Acta 2020, 1111, 16–22.
8. Guoqiang Zhang#, Hua Huang#, Di Liu#, Ying Cheng, Xiaoling Liu, Wenxin Zhang, Ruichuan Yin, Dapeng Zhang, Peng Zhang, Jianzhao Liu, Chaoyi Li, Baodong Liu, Yuewan Luo, Yuanxiang Zhu, Ning Zhang, Shunmin He, Chuan He, Hailin Wang*, Dahua Chen*. N6-Methyladenine DNA modification in Drosophila. Cell 2015, 161, 893–906.
9. Fei Xinrui, Liu Xiaoling*, Liu Chenghui*. The effect of different DNA activator structures on the trans -cleavage activity of Cas12a for in vitro biosensing. Journal of Instrumental Analysis 2022, 41, 610–617.
六、联系方式
通讯地址:陕西省杨凌示范区西农路22号西北农林科技大学 北校区
邮编:712100
邮箱:liuxiaoling@nwafu.edu.cn
欢迎对生命分析化学感兴趣的研究生、本科生加入!