一、个人简介
祁建钊，男，汉族，生于1989年2月，中共党员，副教授，博士生导师。现任西北农林科技大学食用菌中心副主任、陕西省天然产物化学生物学重点实验室秘书。现任中国菌物学会菌物科普导师、陕西省细胞生物学会糖生物学专业委员会常务委员、陕西省食用菌产业技术创新战略联盟专家委员会委员。担任TMR Integrative Medicine编委，Chinese Herbal Medicines， Journal of Exploratory Research in Pharmacology、《菌物研究》、《现代中医药》青年编委。在Cell Chem Bio，J Agri Food Chem等杂志发表论文80多篇，其中第一作者和通讯作者的SCI论文40余篇(中科院二区及以上25篇)，获批授权国家发明专利5项。指导全国大学生生命科学竞赛六次，获国家一等奖、二等奖、三等奖各两次；指导大学生创新创业训练计划国家级项目一项、省级项目三项；指导校级院级本科生优秀毕业论文各一篇。
二、学习与工作经历
1.学习经历
2013年7月硕士毕业于武汉大学遗传学专业，师从朱英国院士。
2016年12月获武汉大学生物化学与分子生物学专业博士学位，师从邓子新院士。
2.工作经历
2017年7月入职西北农林科技大学，从事教学科研工作。
2018年-2019年西北农林科技大学生物学博士后流动站在职博后，合作导师高锦明教授。
2021年-2022年东北林业大学访问学者，合作导师刘成伟教授教授。
三、研究课题
1. 新型表观遗传抗肿瘤药物阿扎胞苷的生物合成研究， 国家自然科学基金，31800031。
2. 细菌中 1.3.5-三嗪环结构单元的生物合成机制研究，中国博士后科学基金，2019M653760。
3. 新型表观遗传抗肿瘤药物阿扎胞苷的产量提高研究与高产菌株构建，陕西省自然科学基金青年项目，2019JQ-046。
4. 蘑菇来源的活性二萜和三萜的合成生物学制造，陕西省重点研发计划，2023-YBSF-164。
5. “小木耳、大产业”关键技术集成及发展模式，陕西省农业核心攻关项目，2023NYGG010-1。
四、研究领域
1．大型真菌(蘑菇)来源天然活性成分的结构鉴定和活性评价。
2．药用真菌活性成分的生物合成与绿色制造。
3．大型真菌种质资源及其遗传进化。
五、开设课程
为本科讲授《分子生物学》、《天然药物生物合成》、《仪器分析》，为研究生讲授《高等分子生物学》、《天然产物的生物合成》。
六、主要科研成果与学术论文
1.近三年主要学术论文（#为共同第一作者，*为通讯作者）
(24). Zhi-xuan Li#, Ming Zhang#, Yu-ying Liu, Minglei Li*, Jianzhao Qi*. Advances in the preparation, structure-activity relationship, and biological mechanisms of Agaricus polysaccharides. Food Science and Human Wellness. 2025, DOI: 10.26599/FSHW.2025.9250590
(23). Zhen-Xin Wang, Kai Huang, Kun-Lun Pu, Ling Li, Wen-Xin Jiang, Jing Wu, Hirokazu Kawagishi, Minglei Li*, Jianzhao Qi*. Food & Medicine Homology, 2025, DOI:10.26599/FMH.2025.9420072
(22). Yu Song, Ming Zhang, Yu-ying Liu, Minglei Li*, Xiu-chao Xie*, Jianzhao Qi*. Haplotype-phased chromosome-level genome assembly of Cryptoporus qinlingensis, a typical traditional Chinese medicine fungus. Journal of Fungi. 2025, 11(2):163. DOI:10.3390/jof11020163
(21). Kai Huang, Ling Li, Weijun Wu, Kunlun Pu, Wei Qi, Jianzhao Qi*, Minglei Li*. Enhancing morchella mushroom yield and quality through the amendment of soil physicochemical properties and microbial community with Wood Ash. Microorganisms, 2024, 23 (12):2406. DOI: 10.3390/microorganisms12122406
(20). Jianzhao Qi*, Y Liu, Jing Wu, Hirokazu Kawagishi, Chengwei Liu*. Bibliometric analysis of Hericium mushrooms for medicinal and food purposes: 1992-2023. Journal of Future Foods, 2024, 5 (4):317-330. DOI:10.1016/j.jfutfo.2024.07.011
(19). Yu-ying Liu, Ming Zhang, Fei Tang, Haiqiang Wang, Jinming Gao, Minglei Li*, Jianzhao Qi*. Exploring the molecular tapestry of Sarcodon secondary metabolites: chemical structures, activities, and biosynthesis. Mycology, 2024,1-22. DOI:10.1080/21501203.2024.2380381
(18). Ming Zhang, Ling Zhao, Fei Tang, Jin-ming Gao, Jianzhao Qi*. Chemical Structures, Biological Activities, and Biosynthetic Analysis of Secondary Metabolites from Agaricus Mushrooms: A Review. Journal of Agricultural and Food Chemistry. 2024, 72(22): 12387-12397. DOI: 10.1021/acs.jafc.4c01861
(17). Xiuchao Xie, Ling Zhao, Yu Song, Yanming Qiao, Zhen-Xin Wang, Jianzhao Qi*. Genome-wide characterization and metabolite profiling of Cyathus olla: insights into the biosynthesis of medicinal compounds. BMC Genomics, 2024,25:618. DOI:10.1186/s12864-024-10528-3
(16). Feng Xi-long, Xie, Tianchen, Wang Zhen-xin, Chao Lin, Zhao-chen Li, Jinxi Huo, Yougui Li, Chengwei Liu, Jin-ming Gao, Jianzhao Qi*. Distinguishing Sanghuangporus from sanghuang-related fungi: a comparative and phylogenetic analysis based on mitogenomes. Appl Microbiol Biotechnol,2024 108, 423. DOI:10.1007/s00253-024-13207-1
(15). Shi-jie Kang, Ling Zhao, Haiqiang Wang, Jin‑ming Gao, Jianzhao Qi*. Chemical structures, biological activities, and biosynthetic analysis of secondary metabolites of the Diatrypaceae family: a comprehensive Review. Mycology. 2024, 15(3), 322-344. DOI:10.1080/21501203.2024.2341648
(14). Jianzhao Qi*, Shi-jie Kang, Ling Zhao, Jin‑ming Gao , Chengwei Liu*. Natural and engineered xylosyl products from microbial source. Natural Products and Bioprospecting. 2024, 14(1):13. DOI: 10.1007/s13659-024-00435-1
(13). Haiyan Han, Shuang Peng, Qian Wang, Hongwei Wang, Pengchao Wang, Chang Li, Jianzhao Qi*, Chengwei Liu*. Biochemical characterization of a multiple prenyltransferase from Tolypocladium inflatum. Applied Microbiology and Biotechnology. 2024, 108(1):275. DOI: 10.1007/s00253-024-13113-6
(12). Jianzhao Qi, Jing Wu, Shi-jie Kang, Jing-ming Gao, Hirokazu Kawagishi*, Hongwei Liu*, Chengwei Liu*. The chemical structures, biosynthesis, and biological activities of secondary metabolites from the culinary-medicinal mushrooms of the genus Hericium : A review. Chinese Journal of Natural Medicines. 2024, 22(8): 676-698. DOI:10.1016/S1875-5364(24)60590-X
(11). Jianzhao Qi, Yu-Qi Gao, Shi-jie Kang, Chengwei Liu*, Jin-Ming Gao*. Secondary metabolites of bird's nest fungi: chemical structures and biological activities. Journal of Agricultural and Food Chemistry. 2023, 71(17):6513-6524. DOI:10.1021/acs.jafc.3c00904
(10). Yu, Chunyan#, Jianzhao Qi#, Haiyan Han, Pengchao Wang*, Chengwei Liu*. Progress in pathogenesis research of Ustilago maydis, and the metabolites involved along with their biosynthesis. Molecular Plant Pathology. 2023, 24, (5): 495-509. DOI:10.1111/mpp.13307
(9). Zhao Chunhua, Xi-long Feng, Zhen-xin Wang, Jianzhao Qi*. The First Whole Genome Sequencing of Agaricus bitorquis and Its Metabolite Profiling. Journal of Fungi. 2023, 9, (4): 485. DOI:10.3390/jof9040485
(8). Feng, Xi-Long#, Rui-Qi Zhang#, Da-Cheng Wang, Wei-Ge Dong, Zhen-Xin Wang, Yi-Jie Zhai, Wen-Bo Han, Xia Yin, Junmian Tian, Jing Wei, Jin-Ming Gao*, Jianzhao Qi*. Genomic and Metabolite Profiling Reveal a Novel Streptomyces Strain, QHH-9511, from the Qinghai-Tibet Plateau. Microbiology Spectrum. 2023, 11, (1): e02764-02722. DOI:10.1128/spectrum.02764-22
(7). Zhang,Wenyu, Ming Yang, Wanlu Li, Lin Zhou, Yaoyao Shen, Shu-Ping Wang, Jin-Ming Gao, Hou-Wen Lin, Jianzhao Qi*, Yongjun Zhou*. Iterative-Acting Thioesterase from Polyketide Biosynthesis Accepts Diverse Nucleophilic Alcohols to Yield Oxazole-Containing Esters. Journal of Agricultural and Food Chemistry. 2023, 71, (19): 7459-7467. DOI:10.1021/acs.jafc.3c00548
(6). Li, Zhao-chen, Tian-chen Xie, Xi-long Feng, Zhen-xin Wang, Chao Lin, Guo-ming Li, Xiu-Zhang Li, Jianzhao Qi*. The First Five Mitochondrial Genomes for the Family Nidulariaceae Reveal Novel Gene Rearrangements, Intron Dynamics, and Phylogeny of Agaricales. International Journal of Molecular Sciences. 2023, 24, (16): 12599. DOI:10.3390/ijms241612599
(5). Wei, Jing, Min Cheng, Jian-fang Zhu, Yilin Zhang, Kun Cui, Xuejun Wang*, Jianzhao Qi*. Comparative Genomic Analysis and Metabolic Potential Profiling of a Novel Culinary-Medicinal Mushroom, Hericium rajendrae (Basidiomycota). Journal of Fungi. 2023, 9, (10). DOI:10.3390/jof9101018
(4). Jianzhao Qi, Haiyan Han, Dan Sui, Shengnan Tan, Changli Liu, Pengchao Wang, Chunliang Xie, Xuekui Xia, Jin-ming Gao*, Chengwei Liu*. Efficient production of a cyclic dipeptide (cyclo-TA) using heterologous expression system of filamentous fungus Aspergillus oryzae. Microbial Cell Factories. 2022, 21, (1): 146. DOI:10.1186/s12934-022-01872-8
(3). Zhang, Ping#, Jianzhao Qi#, Yingce Duan, Jin-Ming Gao*, Chengwei Liu*. Research Progress on Fungal Sesterterpenoids Biosynthesis. Journal of Fungi. 2022, 8, (10): 1080. DOI:10.3390/jof8101080
(2). Zhang, Rui-qi, Xi-long Feng, Zhen-xin Wang, Tian-chen Xie, Yingce Duan, Chengwei Liu*, Jin-ming Gao*, Jianzhao Qi*. Genomic and Metabolomic Analyses of the Medicinal Fungus Inonotus hispidus for Its Metabolite's Biosynthesis and Medicinal Application. Journal of Fungi. 2022, 8, (12) . DOI: 10.3390/jof8121245
(1). Dong, Wei-Ge, Zhen-Xin Wang, Xi-Long Feng, Rui-Qi Zhang, Dao-Yin Shen, Shuangtian Du, Jin-Ming Gao*, Jianzhao Qi*. Chromosome-Level Genome Sequences, Comparative Genomic Analyses, and Secondary-Metabolite Biosynthesis Evaluation of the Medicinal Edible Mushroom Laetiporus sulphureus. Microbiology Spectrum. 2022, 10, (5): e0243922. DOI:10.1128/spectrum.02439-22
2.专利
(1)祁建钊、张文禹，一种含恶唑环的杂合聚酮化合物及其制备方法和应用，2024-02-27. 中国专利，CN202310197787.4
(2) 陈文青、祁建钊、邓子新、刘进，肽基核苷类杂合抗生素Nikkoxin E和Nikkoxin F及其制备方法，2017-04-12，中国专利，CN201510033114. 0
(3)刘成伟、祁建钊、刘长莉，一种利用米曲霉制备L-色氨酸-L.-丙氨酸环:二肽的办法，2022- 08-23，中国专利，202210503663X
(4) 韩文博、翟怡杰、李剑男、王大成、祁建钊、高锦明，一种具有酪氨酸酶抑制活性的聚酮化合物的制备方法及其应用，2023 -02-10，中国专利，CN20201 1209679. 7.
七、联系方式
通讯地址：西北农林科技大学（北校区）化学与药学院C316办公室
邮编：712100
电话：18092036103
邮箱：qjz@nwafu.edu.cn
