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张翔

作者:         来源:         发布日期:2019-12-16     浏览次数:

     

一、个人简介:张翔.png

张翔,男,汉族,1989年8月生,安徽蚌埠人。博士,副教授,硕士生导师。

二、工作经历:

2019.12 - 至今,西北农林科技大学化学与药学院,副教授

2017.08 -2019.07,瑞士日内瓦大学博士后,合作导师:Stefan Matile教授

三、受教育经历:

2012.09 - 2017.07,天津大学,应用化学,工学博士,导师:赵康教授

2008.09 - 2012.07,天津医科大学,药物制剂,理学学士,导师:段宏泉教授

四、研究兴趣:有机合成方法学,杂环化学,活性天然产物及功能分子的合成,弱相互作用下的催化反应

五、科研课题:

西北农林科技大学引进人才启动经费30万元,主持,2019-2024年

六、开设课程:

《有机化学B》(食品科学与工程学院本科生),2020年春

七、主要学术成果

(一)、已发表论文:

1.    Xiang Zhang, Naomi Sakai, Stefan Matile.*Methyl Scanning for MechanochemicalChalcogen-Bonding Cascade Switches. ChemistryOpen 2019, in press (DOI: 10.1002/open.201900288).

2.    Xiang Zhang, Xintong Wan, Ying Cong, Xiaohua Zhen, Qiao Li, Daisy Zhang-Negrerie, Yunfei Du,*Kang Zhao.*Lactonization of 2-Alkynylbenzoates for the Assembly of Isochromenones Mediated by BF3·Et2O.  J. Org. Chem. 2019,  84 , 10402−10411.

3.    Xiang Zhang, XiaoyuHao, Le Liu, Anh-Tuan Pham, Javier López-Andarias, Antonio Frontera, Naomi Sakai, Stefan Matile.* Primary Anion-π Catalysis and Autocatalysis.  J. Am. Chem. Soc . 2018,  140 , 17867−17871.

4.    Xiang Zhang(#), Le Liu (#), Javier López-Andarias, Chao Wang, Naomi Sakai, and Stefan Matile.* Anion-π Catalysis: Focus on Nonadjacent Stereocenters.  Helv.Chim.Acta 2018,  101 , e1700288.

5.    Xiang Zhang, Guangshuai Zhou, Yong Zhang, Daisy Zhang-Negrerie, Yunfei Du,* Kang Zhao.* A Ring-contraction Disproportionation-Spirocyclization Cascade Reaction of Isochromeno [4,3- b ]indol-5(11 H )-ones: Synthesis of  N -UnsubstitutedSpirocycles.  J. Org. Chem. 2016,  81 , 11397.

6.    Xiang Zhang, Ying Cong, KunhuaLei, XuliangGuo, Yang Cao, Kunhua Lei, Yunfei Du.* Recent Advances of the Application of Organoiodine(III) Reagents in the Construction of Heterocyclic Compounds. Chin. J. Org. Chem. 2016,  36 , 2513 (Review, Cover).

7.    Xiang Zhang, WenjuanHou, Daisy Zhang-Negrerie, Kang Zhao, Yunfei Du.* Hypervalent Iodine-Mediated Intramolecular trans -Aminocarboxylation and Oxoaminocarboxylation of Alkynes: Divergent Cascade Annulations of Isocoumarins under Metal-Free Conditions.  Org. Lett.  2015, 17 , 5252−5255 (highlighted by X-mol news, http://www.x-mol.com/news/1517).

8.    Xiang Zhang, Chao Yang, Daisy Zhang-Negrerie, YunfeiDu.* Hypervalent-Iodine-Mediated Cascade Annulation of Diarylalkynes Forming Spiro Heterocycles under Metal-Free Conditions. Chem.−Eur. J . 2015,  21 , 5193−5198 (Hot Paper).

9.    Xiang Zhang, Daisy Zhang-Negrerie, Jun Deng, Yunfei Du,* Kang Zhao.* Synthesis of Diversely Substituted Indoloquinolinones via Pd(II)/Cu(II)-Mediated Oxidative C−C Bond Formation and I(III)-Mediated C−N Bond Formation.  J. Org. Chem. 2013, 78 , 12750−12759 (Abstracted by ChemInform, 2014, DOI: 10.1002/chin.201422168).

10.  Ying Zhou,Xiang Zhang, Daisy Zhang-Negrerie, Yunfei Du.*Iodocyclization of  N -ArylpropynamidesMediated  byHypervaent Iodine Reagent: Divergent Synthesis of Quinolin-2-ones and Spiro[4,5]trienones. ( Org. Lett.  2017 , 19,  150-153)

11.  Yang Cao, Xiang Zhang, Guangyu Lin, Daisy Zhang-Negrerie, Yunfei Du.* Chiral Aryliodine-Mediated EnantioselectiveOrganocatalytic Oxidative Spirocyclization of Spirofurooxindoles via Cascade C-O and C-C Bond Formation.  Org. Lett. 2016, 18 , 5580.

12.  Chao Yang, Xiang Zhang, Daisy Zhang-Negrerie, Yunfei Du,* Kang Zhao.* PhI(OCOCF3)2-Mediated Cyclization of  o -(1-Alkynyl)benzamides: Metal-Free Synthesis of 3-Hydroxy-2,3- dihydroisoquinoline-1,4-dione. J. Org. Chem.  2015 , 80, 5320−5328.

13.  Xuming Li, Liu Yang, Xiang Zhang, Daisy Zhang-Negrerie, Yunfei Du,* Kang Zhao.* Construction of 1,4-Benzodiazepine Skeleton from 2-(Arylamino)benzamides through PhI(OAc)2Mediated Oxidative C−N Bond Formation.  J. Org. Chem.  2014,  79 , 955−962.

14.  Jia Liu, Sheng-Nan Ma, Xiang Zhang, Mei-Na Jin, Mei-Hua Jin, Dexin Kong,* Nan Qin,* Hong-Quan Duan.* Synthesis and Antimetastatic Effect of  E -Salignone.  Chem. Nat. Compd.  2014 , 50, 697−701.

15.  Hong-Ling Wang, Nan Qin, Jia Liu, Mei-Na Jin, Xiang Zhang, Mei-Hua Jin, Dexin Kong, Shen-De Jiang, Hong-Quan Duan.* Synthesis and Antimetastatic Effects of  E -Salignone Amide Derivatives.  Drug Dev. Res.  2014 , 75 , 76–87.

16.  Le Liu, Hang Lu, Hong Wang, Chao Yang, Xiang Zhang, Daisy Zhang-Negrerie, Yunfei Du,* Kang Zhao.*PhI(OCOCF3)2-Mediated C−C Bond Formation Concomitant with a 1,2-Aryl Shift in a Metal-Free Synthesis of 3-Arylquinolin-2-ones. Org. Lett . 2013,  15 , 2906−2909.

(二)、著述章节:

Yunfei Du, Xiang Zhang, Kang Zhao “ e -EROS Electronic Encyclopedia of Reagents for Organic Synthesis”(Phenyliodine(III) Bis(trifluoroacetate)(rp069),Wiley (Latest Version, DOI: 10.1002/047084289X.rp069.pub3).

(三)、授权专利:

Yunfei Du, Xuming Li, Xiang Zhang, Kang Zhao. Synthesis of 1,4-Benzodiazepine Derivatives. Patent, CN201310455049.1, approved on Jan. 5th, 2014.

联系方式

通讯地址:陕西杨凌邰城路22号西北农林科技大学化学与药学院

邮编:712100

电话:13902199949

邮箱:xiang.zhang@nwsuaf.edu.cn

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